Yep, cancer is still complicated

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If you haven’t read The Emperor of All Maladies: A Biography of Cancer by Siddhartha Mukherjee, I would highly recommend it. And if you would rather watch it, Ken Burns produced a documentary focusing on the book that recently aired on PBS.   While we have come a long way in cancer research, it is alarming how little we still know about it.  In the age of personalized medicine and the plethora of cancer datasets, you would think that understanding cancer is getting to be, at the very least, more understandable.  This New York Times opinion article gives a few examples where finding a druggable mutation is not as easy as one would hope.

Trying to Fool Cancer –


Iceland Genetics

Finding genetic outliers becomes an easier task in homogeneous populations.  Iceland is a perfect example.  Article from WIRED.

Why Iceland Is the World’s Greatest Genetic Laboratory | WIRED.

A related article also appeared in NYTimes Science:

In Iceland’s DNA, New Clues to Disease-Causing Genes | NYTimes