Nature recently had a news feature documenting the most popular genes in the human genome by Elie Doglin. In addition to a list of the most popular genes and their location in the human genome, the article discusses the history of popular genes. Genes that became popular signaled new scientific discoveries at the time. This was a fun read.

Source: Peter Kerpedjiev/NCBI-NLM (from The most popular genes in the human genome)